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Search by protein name, UniProt number, IPI number, or 15 AA P-site sequence.
Updated: 2017 Aug. 1
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Warning
– Occasionally the phosphosites shown below in more divergent species may be slightly mis-aligned with our algorithm and the calculated Conservation Score may be higher than shown.
Phosphosite
Conservation Score
Human Protein:
RPS6KB1
All Species:
21.21
Human Site:
S40
Identified Species:
33.33
UniProt:
P23443
Number Species:
14
Phosphosite Substitution
Charge Score:
0.07
Phosphosite
Sequences
Species
Species
Scientific Name
UniProt ID
NCBI Ref Seq ID
AA#
Mr(Da)
P-Site
-7
-6
-5
-4
-3
-2
-1
0
1
2
3
4
5
6
7
Human
Homo sapiens
P23443
NP_003152.1
525
59140
S40
D
Q
P
E
D
A
G
S
E
D
E
L
E
E
G
Chimpanzee
Pan troglodytes
XP_523815
451
50966
D23
F
R
D
R
E
A
E
D
M
A
G
V
F
D
I
Rhesus Macaque
Macaca mulatta
XP_001109701
525
59511
S40
D
Q
P
E
D
A
G
S
E
D
E
L
E
E
G
Dog
Lupus familis
XP_537702
525
59107
S40
D
Q
P
E
D
A
G
S
E
D
E
L
E
E
G
Cat
Felis silvestris
Mouse
Mus musculus
Q8BSK8
525
59199
S40
D
Q
P
E
D
A
G
S
E
D
E
L
E
E
G
Rat
Rattus norvegicus
P67999
525
59113
S40
D
Q
P
E
D
A
G
S
E
D
E
L
E
E
G
Wallaby
Macropus eugenll
Platypus
Ornith. anatinus
XP_001509850
482
54026
M23
V
G
P
Y
E
L
G
M
E
H
C
E
K
F
E
Chicken
Gallus gallus
P18652
752
84421
K38
G
N
P
P
C
K
A
K
S
D
I
T
W
V
E
Frog
Xenopus laevis
P10666
629
71268
G25
E
D
T
E
N
G
H
G
G
P
E
D
R
G
R
Zebra Danio
Brachydanio rerio
Q6PFQ0
740
83378
N24
Q
S
V
S
S
E
V
N
G
H
Q
I
M
D
E
Tiger Blowfish
Takifugu rubipres
Fruit Fly
Dros. melanogaster
Q9V3I5
1207
137026
A205
A
A
A
A
A
A
A
A
A
S
K
A
S
S
S
Honey Bee
Apis mellifera
XP_395876
456
51514
E26
E
S
D
D
D
V
I
E
I
G
E
V
I
L
H
Nematode Worm
Caenorhab. elegans
Q21734
784
88102
T53
P
T
D
C
S
S
D
T
T
N
T
F
H
S
S
Sea Urchin
Strong. purpuratus
XP_781234
487
53968
S26
A
N
E
C
L
S
D
S
D
D
M
Q
D
E
G
Poplar Tree
Populus trichocarpa
Maize
Zea mays
Rice
Oryza sativa
Thale Cress
Arabidopsis thaliana
Q39030
471
53019
P29
L
S
L
S
I
S
P
P
K
S
V
L
G
D
N
Baker's Yeast
Sacchar. cerevisiae
Red Bread Mold
Neurospora crassa
Conservation
Percent
Protein Identity:
100
85.9
94.2
99.8
N.A.
99.2
99.6
N.A.
90.2
31.9
36.8
32.2
N.A.
20.8
54.6
31.2
59
Protein Similarity:
100
85.9
95.6
100
N.A.
99.4
99.6
N.A.
90.8
46.6
52.7
46.6
N.A.
31.3
68
43.6
70.8
P-Site Identity:
100
6.6
100
100
N.A.
100
100
N.A.
20
13.3
13.3
0
N.A.
6.6
13.3
0
26.6
P-Site Similarity:
100
33.3
100
100
N.A.
100
100
N.A.
33.3
13.3
26.6
26.6
N.A.
20
33.3
20
46.6
Percent
Protein Identity:
N.A.
N.A.
N.A.
36.3
N.A.
N.A.
Protein Similarity:
N.A.
N.A.
N.A.
55
N.A.
N.A.
P-Site Identity:
N.A.
N.A.
N.A.
6.6
N.A.
N.A.
P-Site Similarity:
N.A.
N.A.
N.A.
26.6
N.A.
N.A.
Phosphosite
Consensus
Position
-7
-6
-5
-4
-3
-4
-5
0
+1
+2
+3
+4
+5
+6
+7
% Ala:
14
7
7
7
7
47
14
7
7
7
0
7
0
0
0
% A
% Cys:
0
0
0
14
7
0
0
0
0
0
7
0
0
0
0
% C
% Asp:
34
7
20
7
40
0
14
7
7
47
0
7
7
20
0
% D
% Glu:
14
0
7
40
14
7
7
7
40
0
47
7
34
40
20
% E
% Phe:
7
0
0
0
0
0
0
0
0
0
0
7
7
7
0
% F
% Gly:
7
7
0
0
0
7
40
7
14
7
7
0
7
7
40
% G
% His:
0
0
0
0
0
0
7
0
0
14
0
0
7
0
7
% H
% Ile:
0
0
0
0
7
0
7
0
7
0
7
7
7
0
7
% I
% Lys:
0
0
0
0
0
7
0
7
7
0
7
0
7
0
0
% K
% Leu:
7
0
7
0
7
7
0
0
0
0
0
40
0
7
0
% L
% Met:
0
0
0
0
0
0
0
7
7
0
7
0
7
0
0
% M
% Asn:
0
14
0
0
7
0
0
7
0
7
0
0
0
0
7
% N
% Pro:
7
0
47
7
0
0
7
7
0
7
0
0
0
0
0
% P
% Gln:
7
34
0
0
0
0
0
0
0
0
7
7
0
0
0
% Q
% Arg:
0
7
0
7
0
0
0
0
0
0
0
0
7
0
7
% R
% Ser:
0
20
0
14
14
20
0
40
7
14
0
0
7
14
14
% S
% Thr:
0
7
7
0
0
0
0
7
7
0
7
7
0
0
0
% T
% Val:
7
0
7
0
0
7
7
0
0
0
7
14
0
7
0
% V
% Trp:
0
0
0
0
0
0
0
0
0
0
0
0
7
0
0
% W
% Tyr:
0
0
0
7
0
0
0
0
0
0
0
0
0
0
0
% Y
% Spaces:
0
0
0
0
0
0
0
0
0
0
0
0
0
0
0
% _